| ncRNA name | hsa-miR-24 |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | human RB cell lines WERI-RB1; human embryonic kidney cell lines HEK293 and HEK293T; human ovarian cancer cell lines SKOV3 and OVCAR-3; human cervical cancer cell line HeLa; human osteosarcoma cell line SaOS2 |
| Methods | RT-PCR, qPCR, Western blot, immunostaining, siRNA transfection |
| Expression pattern | up-regulated |
| Functional description | miR-24 could functionally repress expression, effectively blocking p53 tumor surveillance. During retinal tumorigenesis, miR-24 may intrinsically compromise the p53 response to RB1 loss. |
| PubMed ID | 22336108 |
| Year | 2012 |
| Title | Regulation of p14ARF expression by miR-24: a potential mechanism compromising the p53 response during retinoblastoma development. |
| Drug-related ncRNA | NO |
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